Scientific Program – Wednesday


7:00-8:00 Coffee & Tea Served Vide Foyer
Plenary RCTs
Moderators: B Kavanagh, N Ferguson
Grand EAST
7:30-7:45 The BiRDS Trial – Early Spontaneous Breathing in ARDS JC Richard
7:45-7:50 Editorial Comment G Bellani
7:50-8:00 Questions and Discussion
8:00-8:15 EPVENT2 Trial – Esophageal Pressure in ARDS D Talmor
8:15-8:20 Editorial Comment M Amato
8:20-8:30 Questions and Discussion
8:30 Presentation of the 2018 Global Sepsis Alliance Award to Dr. A Fox-Robichaud
Sepsis I – Mechanistic Insights
Moderators: M Shankar-Hari, J Bubeck-Wardenberg
Grand EAST
8:30-8:50 Myths, dogma and misconceptions in sepsis M Singer
8:50-9:20 The mitochondria in sepsis J Fraser
9:20-9:40 Lipoproteins in sepsis K Walley
9:40-9:50 Molecular subclasses of sepsis H Wong
9:50-10:00 Discussion
Spontaneous Breathing with Mechanical Ventilation
Moderators: T Piraino, M Schultz
8:30-8:50 The Dark Side of Spontaneous Breathing T Yoshida
8:50-9:10 Safe Spontaneous Breathing E Goligher
9:10-9:30 Plateau and driving pressure during spontaneous breathing G Bellani
9:30-9:50 Respiratory Mechanics to deliver a safe ventilation in ARDS L Brochard
9:50-10:00 Discussion
ATS Workshop – The Research Agenda for Precision Medicine in ARDS & Sepsis: Identifying Endotypes in Sepsis & ARDS
Moderators: S Yende, E Azoulay
Grand WEST
8:30-8:50 Using Observational and RCT Databases to identify endotypes P Sinha
8:55-9:15 Integrating omics platforms and using EHR to identify endotypes (Simplifying complex data for RCTs) A Gordon
9:20-9:40 Statistical approaches to identify endotypes G Clermont
9:45-10:00 Group discussion for all panelists
CIHR-CCCS Forum – Creating a Diverse and Inclusive Research & Training Environment: Addressing Diversity Issues in Training & Research
Moderators: D Piquette, A Leligdowicz
Sheraton AB
8:30-8:40 Welcome and Opening Blessing K Burns;  R Perry
8:40-9:05 Sex & Gender Equality Policy in Research Funding C Tannenbaum
9:15-9:30 Professional Societies in Equity & Diversity Issues A Fox-Robichaud
9:35-10:00 Trainee Abstract Discussion Facilitators: G Vazquez & C Gomez
9:35-9:40 Oral Abstract: Gender disparity in CCM Research G Xu
9:45-9:50 Oral Abstract: Gender and Evaluation in CCM J Spring
9:50-10:00 Discussion
10:00-10:30 BREAK
All about the PEEP
Moderators: C Hough, E Goligher
Grand EAST
10:30-10:50 Bedside PEEP setting by EIT G Bellani
10:50-11:10 Eye-opening reanalysis of the ART trial M Amato
11:10-11:30 PEEP can adversely affect the right heart A Vieillard-Baron
11:30-11:50 CNAP is better than PEEP T Yoshida
11:50-12:00 Discussion
Protecting and Preserving the Injured Brain
Moderators: G Boyd, A Baker
10:30-10:50 Rethinking neuroprotection in acute brain injury V McCredie
10:50-11:10 Glucose and the brain in ICU: hyper versus hypo? G Van den Berghe
11:10-11:30 Should a decompressive craniectomy ever be done in TBI? A Turgeon
11:30-11:50 Suspended animation for ischaemia-reperfusion injury M Singer
11:50-12:00 Discussion
ATS Workshop – The Research Agenda for Precision Medicine in ARDS & Sepsis: Organizing & Sustaining Precision Platforms
Moderators: N Meyer, N Ferguson
Grand WEST
10:30-10:50 Identifying and validating biomarkers for multicenter RCTs H Wong
10:55-11:15 Learning from breast cancer and stroke C Calfee
11:20-11:40 Novel funding mechanisms to sustain precision medicine platforms N Aggarwal
11:40-12:00 Group discussion for all panelists
CIHR-CCCS Investigator Forum – Creating a Diverse and Inclusive Research & Training Environment: Indigenous Peoples’ Issues in Training & Research
Moderators: M Sen, A Mendelson
Sheraton AB
10:30-10:50 Walking the Road of a Researcher Ally P Camp
11:00-11:15 Iterative Peer Review for Indigenous Health Research L Richardson
11:20-11:35 Indigenous Patients’ Healthcare Experience After Overdose M St. Onge
11:35-12:00 Abstract Discussion Facilitators: A Binnie & M Peretz-Larochelle
11:35-11:40 Oral Abstract: Social Determinants and Critical Events D Lee
11:45-11:50 Oral Abstracts: Ethnicity and Care Limitation in CCM C Yarnell
11:55-12:00 Closing Remarks A Fox-Robichaud; R Perry
12:00-13:00 CCCS AGM    
12:00-13:00 LUNCH
Plenary Session: Threats to the Concept of Brain Death
Moderators: N Ferguson, B Kavanagh
Grand EAST
13:00-13:05 Case Presentation B Kavanagh
13:05-13:20 Medical – Death is Not Brain-based A Joffe
13:20-13:35 Medical – Death is Brain-based S Shemie
13:35-13:50 Legal Uncertainty H Scher
13:50-14:05 Legal Coherence D Jarvis
14:05-14:20 Ethical Reflections R Sibbald
14:20-14:35 International Perspectives D Greer
14:35-15:00 Panel Discussion and Audience Questions
15:00 – 15:30 PM BREAK
Organ Donation I
Moderators: S Dhanani, S Beed
Panelists: M Thompson, D Greer, A Healey, J Singh, M Weiss
Grand EAST
15:30-15:50 Changing Demographics in Death After Devastating Brain Injury A Kramer
15:50-16:10 The Opiate Epidemic and Organ Donation S Keenan
16:10-16:50 Death Determination: Challenging Cases Panel
16:50-17:00 Discussion
Critical Care Cardiology
Moderators: D Talmor, G Douflé
15:30-15:50 High dose GIK therapy for low output shock M Singer
15:50-16:10 The right ventricle: from physiology to clinical application A Vieillard-Baron
16:10-16:30 Who cares about the diastolic pressure? S Magder
16:30-16:50 Cardiopulmonary interaction during CPR J-C Richard
16:50-17:00 Discussion
Sepsis II – Emerging Therapies
Moderators: A Kumar, P Marik
Grand WEST
15:30-15:50 New frontiers for antibiotics A Torres
15:50-16:10 New frontiers for IVIG in sepsis M Shankar-Hari
16:10-16:30 VA ECMO for septic shock A Combes
16:30-16:50 Cellular Immunotherapy in Sepsis C dos Santos
16:50-17:00 Discussion
Engaging Patients and the ICU Team
Moderators: R Fowler, K Fiest
Sheraton AB
15:30-15:50 An international perspective on interprofessional rounds A Amaral
15:50-16:10 ICU teams and implementation science D Costa
16:10-16:30 Engaging patients and families in critical care research K Fiest
16:30-16:50 The New PICU – from a Toxic to Healing Environment K Choong
16:50-17:00 Discussion
Plenary Address – Novel Sepsis Treatment
Moderators: G Van den Berghe, E Wilcox
Grand EAST
17:00-17:40 Hydrocortisone, Vitamin C and Thiamine for Septic Shock P Marik
17:40-17:50 Not so fast – we need more data N Adhikari
17:50-18:00 Questions and Discussion
18:00-19:00 Welcome Reception Exhibit Hall